Impact of harmonization on predicting complications in head and neck cancer after radiotherapy using MRI radiomics and machine learning techniques.
Our study highlights the importance of harmonization techniques in improving the performance of predictive models utilizing magnetic resonance imaging radiomics features. While harmonization consistently enhanced performance for sticky saliva and early xerostomia using T 1 $T_1$ -weighted features, the prediction of early and late xerostomia using T 2 $T_2$ -weighted features remains challenging. These findings try to develop accurate and reliable predictive models in medical imaging, that contribute to improve patient care and treatment outcomes.