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Цитопении и ПНГ

Медицинские публикации по различного рода цитопениям, апластической анемии и пароксизмальной ночной гемоглобинурии.

Thrombotic Thrombocytopenic Purpura: A Missed Cause in Stroke Prevention Guidelines.

The 2024 Guidelines for the Primary Prevention of Stroke, recently updated by the American Heart Association and the American Stroke Association, serve as an essential resource for clinicians aiming to reduce the growing impact of cerebrovascular disease...

DOI: 10.1161/STROKEAHA.124.049952

Picod A, Joly BS, Veyradier A, Coppo P

Stroke, 2025-04-03

НОВАЯ СТАТЬЯ

Elderly Patients With Aplastic Anemia: Treatment Patterns and Outcomes in the Real World.

We retrospectively analyzed a large international cohort of 1113 patients with aplastic anemia to evaluate treatment choice and outcome in elderly patients as compared with a younger population...

DOI: 10.1002/ajh.27611

Fattizzo B, Gurnari C, Giammarco S, Ricchiuti A, Awada H, Bortolotti M, Galli N, Pedone GL, Versino F, Consonni D, Trikha R, Gandhi S, Sica S, Maciejewski JP, Kulasekararaj A, Barcellini W

American journal of hematology, 2025-04-03

НОВАЯ СТАТЬЯ

Clinical outcomes in critically ill children on extracorporeal membrane oxygenation with severe thrombocytopenia.

IntroductionAs international guidelines suggest keeping the platelet count between 50 and 100 × 109 cells/L in children on extracorporeal membrane oxygenation (ECMO), platelet transfusions are administered to two-thirds of ECMO days, and up to 70% of these patients still bleed...

DOI: 10.1177/02676591241247981

Labarinas S, Norbisrath K, Johnson D, Meliones J, Greenleaf C, Salazar J, Karam O

Perfusion, 2025-04-03

Comparison of Hetrombopag and Eltrombopag Added to First-Line Immunosuppressive Therapy in Severe Aplastic Anemia.

The addition of HPAG to standard IST in SAA patients showed similar response rates and response quality to that of EPAG. HPAG could be an alternative to EPAG for the first-line treatment of SAA patients.

DOI: 10.1111/ejh.14418

Zhang B, Yang W, Kang R, Shi Y, Hu X, Zhang L, Jing L, Yuan W, Shi J, Zhang F, Zhao X

European journal of haematology, 2025-04-02

Successful rechallenge of rifabutin in rifampicin-induced thrombocytopenia during TB treatment.

У данной статьи нет абстракта.

DOI: 10.5588/ijtld.24.0508

Nelson RR, Louw VJ, Curtis B, Peter J

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2025-04-02

A Descriptive 5-Year Analysis of the Demographics and Therapies for Patients With Immune Thrombotic Thrombocytopenic Purpura in the USA: A Multicenter Study of 390 Disease Episodes From 2017 to 2021.

Immune thrombotic thrombocytopenic purpura (iTTP) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and microvascular occlusion secondary to acquired ADAMTS13 deficiency...

DOI: 10.1002/jca.70017

Jacobs JW, Adkins BD, Booth GS, Stanek CG, Allen ES, Grossman BJ, Stephens LD, Crowe EP, Daou L, Marques MB, Siniard RC, Wallace LR, Yamada C, Duque MA, Wu Y, Aljuboori O, Harrington TJ, Byrnes DM, Eichbaum Q, Figueroa Villalba CA, Juskewitch JE, Kla

Journal of clinical apheresis, 2025-04-03

Utility of Thrombopoietin Receptor Agonists for Prolonged Thrombocytopenia After Chimeric Antigen Receptor T-cell Therapy.

Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment landscape for various hematological malignancies...

DOI: 10.1016/j.jtct.2025.01.887

Waddell D, Collins J, Sadrameli S

Transplantation and cellular therapy, 2025-04-03

Metabolomics Analysis Using Chromatography-Mass Spectrometry to Investigate the Mechanism of Cyclosporine in the Treatment of Aplastic Anemia.

Significant differences in metabolites were observed between AA patients and healthy individuals, suggesting that immune-related and energy metabolism pathways may be key targets in AA treatment. CsA intervention in AA may be achieved through the regulation of immune-related metabolic pathways.

DOI: 10.1002/rcm.9968

Guo MX, Wan L, Sun X, Zhou XH, Fang WT, Sun ZZ, Hu ZQ, Xue LL

Rapid communications in mass spectrometry : RCM, 2025-04-01

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