Chloride mass transfers during continuous veno-venous hemodialysis with regional citrate anticoagulation: effects of additional ultrafiltration and Hamburger's effect.
Plasma chloride mass removal during CVVHD-RCA is significantly greater than what is accounted for by dialysate-based loss, suggesting that plasma chloride is transferred to an intracellular compartment. Furthermore, to account for the online administration of citrate and CaCl2 solutions, CVVHD-RCA applies additional ultrafiltration, which significantly contributes to chloride removal from plasma water.